Sanguinarine (pseudochelerythrine) from Macleaya cordata Extract


Sanguinarine (pseudochelerythrine) from Macleaya cordata Extract

Product Name:
Macleaya cordata Extract

Latin Name:
Macleaya cordata (Willd.)

Part Used:
Fruit

Active Ingredients:
Sanguinarine chelerythrine protopine|?-Allocryptopine |?-Allocrytopine Bocconine

Description:

Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-kappaB activation, IkappaBalpha phosphorylation, and degradation.

Macleaya cordata contains several alkaloids including sanguinarine, chelerythrine, protopine, and allocryptopine.Our product, Macleaya cordata extract mainly constains with sanguinarine and chelerythrine.It was been show to be reversible inhibitors of the enzymatic hydrolysis of acetylthiocholine.

It was reported that a study was made of a possible inhibitory action on the enzymatic hydrolysis of acetylthiocholine by human erythrocyte acetylcholinesterase of principal alkaloids isolated from Chelidonium majus L. and Macleaya cordata and microcarpa,and of drugs Ukrain and Sanguirythrine. Among all examined agents berberine, sanguinarine and Sanguirythrine were the strongest inhibitors of this reaction.Judging from the data obtained, sanguinarine and chelerythrine exert similar inhibitory effects on the reaction of enzymatic hydrolysis of acetylthiocholine.