Raspberry ketone is a natural phenolic compound that is the primary aroma compound of red Raspberries. It is used in perfumery, in cosmetics, and as a Food Additive to impart a fruity odor. It is one of the most expensive natural flavor components used in the food industry.
Since the natural abundance of raspberry ketone is very low, it is prepared industrially by a variety of methods from chemical intermediates.One of the ways this can be done is through a crossed aldol-catalytic hydrogenation. In acetone and sodium hydroxide, 4-hydroxybenzaldehyde can form the α,β-unsaturated ketone. This then goes through catalytic hydrogenation to produce raspberry ketone. This method produces a 99% yield.
When given to mice in high doses (up to 2% of food intake), raspberry ketone has been shown to prevent high-fat-diet-induced elevations in body weightThis effect is reported to stem from the alteration of lipid metabolism, increasing norepinephrine-induced lipolysis. Although products containing this compound are marketed for weight loss, this effect has not been studied in humans.
Application:
1.Raspberries have been used throughout history as a supplement, as well as in many medicines.
2.Raspberries are known to be high in antioxidants, which help to keep the body functioning
properly despite the advance of age.
3.Raspberries have also been thought to help relax the blood vessels, which can help to avoid
heart problems and other disorders.
4.Raspberry Ketone has led to an interesting conclusion that raspberries may be a good source
of nutrients that can help lead to weight loss.
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