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1.Greyish-yellow or light yellow Hygroscopic Powder
2.HPLC 90%
3.CAS NO.:520-27-4
4.C28H32O15
5.25kg in drums
Diosmin
Diosmin is a type of plant chemical found mainly in Citrus fruits. People use diosmin to make medicine.
Diosmin is used for treating various disorders of blood vessels including hemorrhoids, varicose veins, poor circulation in the legs (venous stasis), and bleeding (hemorrhage) in the eye or gums. It is also used to treat swelling of the arms (lymphedema) following breast cancer surgery, and to protect against liver toxicity. It is often taken in combination with hesperidin, another plant chemical.
Characters Appearance
Solubility: |
Greyish-yellow or light yellow Hygroscopic powder Practically insoluble in water, soluble in dimethyl sulphoxide, practically insoluble in alcohol, It dissolves in dilute solutions of alkali hydroxides |
Identification A. Infrared absorption spectrophotometry(2.2.24) B.Examine the chromatorgrams obtained in the Assay |
Comparaison diosmin CRS The principal peak in the chromatorgram obtained with the test solution issimilar in retention time and size to the principal peak in the chromatogram obtained withreference solution(a) |
Tests Iodine(2.2.36)&(2.5.10) : Related substances (HPLC)(2..2.29) Impurity A: acetoisovanillone Impurity B: hesperidin Impurity C: isorhoifin Impurity E: linarin Impurity F: diosmitin Others impuritys Total others impuritys and impurity A Total impuritys Heavy metals (2.4.8) Water(2.5.12) Sulphated ash(2.4.14) |
≤0.1%
≤1.0% ≤5.0% ≤3.0% ≤3.0% ≤3.0% ≤1.0% ≤1.0% ≤10.0% 20ppm ≤6.0% ≤0.2% |
Assay(HPLC),anhydroussubstance(2.2.29) |
90%--102% |
Residual Solvents(2.4.24) -Methanol -Ethanol -Pyridine |
≤3000ppm ≤5000ppm ≤200ppm |
Microbilogical Tests (2.6.12)&(2.6.13) Total Plate Count Yeasts and Molds Salmonella E.Coliform |
<10 3 /g <10 2 /g Negation in 1g Negation in 1g |
Type: |
Herbal Extract
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Variety: |
Japanese pagoda tree
|
Form: |
Powder
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Part: |
Buds
|
Extraction Type: |
Solvent Extraction
|
Packaging: |
Drum
|
Place of Origin: |
Shaanxi China (Mainland)
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Grade: |
Pharmaceutical grade
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Brand Name: |
Xi'an Rainbow
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Model Number: |
Diosmin EP
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